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Many people with autoimmune diseases may struggle to fully understand their condition. They know they’ve been diagnosed with an autoimmune disease, but they may not know exactly what it is, what causes it, or how they can address it and possibly reverse some of the damage. Let’s break down what autoimmune diseases are, what causes them, and the steps you can take to manage or even reverse the effects, including how a simple test and a daily supplement could make a significant difference in your health journey.

What Are Autoimmune Diseases?

Autoimmune diseases occur when your immune system mistakenly attacks your own body, thinking that its healthy cells and tissues are foreign invaders. Normally, your immune system defends your body against harmful things like viruses and bacteria. But in autoimmune conditions, the body’s defense system turns on itself, leading to inflammation, tissue damage, and a variety of symptoms depending on which part of the body is being attacked.

Some common autoimmune diseases include rheumatoid arthritis, lupus, multiple sclerosis, type 1 diabetes, Crohn’s disease, and Hashimoto’s thyroiditis. While there’s no single cause for autoimmune diseases, several factors can contribute to their development.

The Causes: Genetics, Environment, and More

The causes of autoimmune diseases are complex. Genetics may play a role, meaning if you have a family history of autoimmune conditions, or inherited lifestyle habits you might be more prone to developing one yourself. However, environmental triggers are often the tipping point. These triggers can include things like:

• • Infections: Certain viral or bacterial infections can trigger autoimmune diseases by confusing the immune system.
  • Chronic stress: Long-term stress can weaken the immune system and lead to an overactive immune response.
  • Dietary choices: Eating inflammatory foods, such as highly processed foods, can worsen autoimmune symptoms.
  • Toxins: Environmental toxins, such as pesticides or pollution, can also play a role.

In addition to these environmental factors, omega-3 fatty acids play a crucial role in preventing and modulating immune system function. Omega-3s, particularly DHA (docosahexaenoic acid), help regulate the immune system and reduce chronic inflammation. Insufficient intake of omega-3s over time can disrupt this balance, increasing the risk of autoimmune diseases. Omega-3s are known to produce anti-inflammatory compounds that help resolve inflammation in the body, and when they are lacking, the immune system may become overactive, contributing to autoimmune conditions.

While autoimmune diseases have no simple, one-size-fits-all solution, managing them involves addressing these environmental triggers and providing your body with the right support to regulate its immune system more effectively.

1. Rigid Cell Membranes and Compromised Mitochondrial Efficiency

Cell membranes are made up of proteins, lipids (fats), and carbohydrates, with special mention of omega-3 fatty acids, especially DHA (docosahexaenoic acid), which are crucial for keeping these membranes flexible. When omega-3s are deficient, cell membranes become rigid, making it harder for cells to take in nutrients and expel waste. This rigidity also affects mitochondrial function, as mitochondria rely on fluid, healthy membranes to produce ATP (adenosine triphosphate), which is the energy currency of the cell. ATP is essential for powering cellular processes, including tissue repair and maintaining cellular health. Reduced ATP production leads to cellular dysfunction, decreased energy levels, and a compromised ability to heal and repair tissue, which can increase the risk of inflammation and autoimmune attacks over time.

2. Chronic Inflammation

Omega-3 fatty acids are well-known for their anti-inflammatory properties. They help produce compounds called resolvins and protectins, which work to resolve inflammation in the body. When omega-3 levels are low, the body relies more on omega-6 fatty acids, which are pro-inflammatory. This imbalance, where omega-6s outnumber omega-3s (as is common in modern diets), leads to an ongoing state of inflammation that is often the underlying cause of many autoimmune diseases.

3. The Role of Polyphenols

In addition to omega-3s, polyphenols (especially those found in unripe olives, berries, and other antioxidant-rich foods) have a profound effect on reducing inflammation and oxidative stress. Polyphenols help stabilize omega-3s, enhancing their effectiveness and absorption into cell membranes. Without sufficient polyphenols, the body becomes more prone to oxidative damage and inflammation, both of which contribute to autoimmune conditions and other chronic diseases.

Understanding Mitochondria and What They Need to Thrive

Mitochondria are specialized organelles within your cells that produce energy in the form of ATP. These organelles are essential for all cellular functions, from muscle contraction to the synthesis of proteins and DNA repair. In fact, the energy produced by mitochondria fuels almost every process in the body. Because of their central role in energy production, healthy mitochondria are crucial for overall health and particularly for immune system function.

For mitochondria to thrive, they require several key nutrients and conditions:

1. 1. Omega-3 Fatty Acids: Omega-3s, particularly DHA, support mitochondrial membrane fluidity, ensuring that mitochondria can function efficiently and effectively produce ATP.
   2. Coenzyme Q10 (CoQ10): This antioxidant plays a vital role in the mitochondrial energy production process, helping to convert nutrients into usable energy for the cell.
   3. B Vitamins: B vitamins, particularly B1, B2, B3, and B5, are necessary for mitochondrial energy production, assisting in the conversion of food into ATP.
   4. Polyphenols: These plant compounds help protect mitochondria from oxidative stress, which can damage mitochondrial function over time.
   5. Proper Oxygen Supply: Mitochondria rely on a steady supply of oxygen to produce ATP through a process called oxidative phosphorylation. Without enough oxygen, mitochondrial function can become compromised.
   6. Exercise and Healthy Lifestyle: Regular physical activity supports mitochondrial biogenesis—the process by which new mitochondria are created—thus improving overall energy production and mitochondrial health.

Mitochondrial dysfunction is linked to numerous health problems, including chronic inflammation, fatigue, and autoimmune diseases. By ensuring that mitochondria have the right nutrients and conditions to thrive, you can enhance cellular energy production, reduce inflammation, and better manage autoimmune conditions.

Reversing or Managing Autoimmune Diseases: A Key Focus on Lifestyle

Although autoimmune diseases are often considered lifelong conditions, it’s important to know that lifestyle changes can significantly improve symptoms and even reverse some of the damage in certain cases. This includes:

1. 1. Optimizing Gut Health:
      The gut plays a huge role in regulating the immune system. A healthy gut microbiome is key to reducing inflammation and preventing the immune system from attacking the body. Probiotics, fiber-rich foods, and avoiding inflammatory foods can help improve gut health.
   2. Reducing Inflammation:
      Chronic inflammation is a hallmark of autoimmune diseases. Anti-inflammatory foods, such as omega-3-rich foods, leafy greens, and polyphenol-rich fruits and vegetables, can help reduce inflammation.
   3. Managing Stress:
      Chronic stress weakens the immune system, so managing stress through techniques like mindfulness, meditation, and yoga can be beneficial.
   4. Improving Nutrition Habits:
      A nutrient-dense diet rich in whole foods, healthy fats, and antioxidants can support the immune system and help reduce symptoms of autoimmune diseases.

The Crucial Test: A DBS Test for Immune Health

One of the most important steps anyone with an autoimmune disease can take is to understand the state of their immune system and its function. That’s why a DBS (Dried Blood Spot) Test is a key tool for autoimmune sufferers. The DBS test is a simple, at-home test that provides a snapshot of your inflammatory markers and can give you valuable insight into your immune system’s health. By understanding your immune system’s baseline, you can make better-informed decisions on how to improve your health.

The DBS test can help you understand inflammation levels in your body, providing key information about your health status. With autoimmune diseases being so closely tied to inflammation, it’s crucial to know where you stand. This test can provide valuable data, allowing you to tailor your approach to managing your autoimmune condition.

Our BalanceTest includes a DBS test. You can schedule a free consultation to learn more and get the test. For more information or to contact me about the test, email Robert@dietfreelife.com.

The Key Supplement: BalanceOil+

Incorporating BalanceOil+ into your daily routine can make a world of difference when managing an autoimmune disease. What sets BalanceOil+ apart from other fish oil or omega-3 supplements is its unique combination of high-quality omega-3s and polyphenols, specifically designed to reduce inflammation, support the immune system, and help improve cellular health.

Omega-3 fatty acids have been shown to reduce inflammation, a key factor in many autoimmune diseases. However, most fish oil supplements lose the valuable polyphenols during the purification process. BalanceOil+, on the other hand, infuses unripe olive polyphenols into the oil. These polyphenols act as a protective ‘chaperone,’ stabilizing omega-3s and enhancing their absorption into tissues and cell membranes, ensuring maximum benefits for your health.

For those with autoimmune diseases, BalanceOil+ is an essential daily supplement because it helps reduce the inflammation that exacerbates symptoms. The combination of omega-3s and polyphenols also supports the body’s ability to heal, recover, and protect against further damage.

The reason we know BalanceOil+ is unquestionably the best is because of the DBS test. I’ve had many clients swear by their supplement until we do the DBS test. It’s at this point that confirmation bias is removed, and the proof is in the results.

Conclusion

Autoimmune diseases are complex, but understanding what they are, their causes, and how you can manage them can empower you to take control of your health. The first step is recognizing that managing inflammation is crucial. The DBS test provides critical insight into your body’s inflammation levels, and BalanceOil+ offers a powerful solution to reduce that inflammation and support your immune system.

By addressing underlying causes, optimizing your gut health, reducing stress, and incorporating omega-3s and polyphenols into your routine, you can manage your autoimmune disease and possibly reverse some of its effects. Taking control of your health is possible, and these steps are an excellent way to start your journey toward feeling better and improving your overall well-being.

Make the commitment to prioritize your health—schedule a consultation to learn more about how you can manage your autoimmune disease, optimize your nutrition, and start reversing symptoms today.

References

1. 1. Calder, P. C., & Yaqoob, P. (2009). Omega-3 polyunsaturated fatty acids and human health: From the Omega-3 index to anti-inflammatory actions. European Journal of Clinical Nutrition, 63(6), 779-788.
   2. De Caterina, R., & Gesualdo, F. (2014). The role of omega-3 fatty acids in the treatment of autoimmune diseases. Nutrition, Metabolism & Cardiovascular Diseases, 24(7), 701-709.
   3. Whelan, J., & Fritsche, K. L. (2002). Polyphenols and their health effects. Journal of the American College of Nutrition, 21(3), 239-249.
   4. Kummerow, F. A. (2016). The role of omega-3 and omega-6 fatty acids in the prevention of cardiovascular disease and the promotion of good health. Journal of Lipid Research, 57(10), 1749-1757.
   5. Salazar, M. F., & Rojas, A. (2021). The impact of omega-3 and polyphenol supplementation on the gut microbiome and its connection to immune health. Frontiers in Immunology, 12, 687.

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Robert Ferguson is a California- and Florida-based single father of two daughters, nutritionist, researcher, best-selling author, speaker, podcast and television host, health advisor, NAACP Image Award Nominee, creator of the Diet Free Life methodology, Chief Nutrition Officer for iCoura Health, and he serves on the Presidential Task Force on Obesity for the National Medical Association. You can e-mail Robert at robert@dietfreelife.com.

🗓️ Schedule a FREE consultation with Robert Ferguson about becoming a client: SCHEDULE FREE CONSULTATION

👉🏽 To order ONLY the BalanceOil+, > CLICK HERE

👉🏽 To order the BalanceOil+ with the BalanceTEST, > CLICK HERE

👉🏽 Watch a free online presentation on the BalanceOil+ and the BalanceTEST: WATCH NOW.

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After a long and draining day of tackling errands, nothing feels better than collapsing into bed for some much-needed rest. But for some, the comfort of sleep is out of reach. Instead, bedtime brings an uncomfortable tingling sensation in the legs and an overwhelming urge to jump out of bed and walk around.

If this sounds familiar, you may be dealing with Restless Leg Syndrome (RLS)—a condition that makes restful sleep a challenge for millions of people. But what does the term syndrome really mean? It’s important to understand that the word “syndrome” indicates that the exact cause of the condition isn’t completely clear. In the case of RLS, researchers have identified links to iron deficiency, dopamine imbalances, and other factors, but the full picture of what causes it remains uncertain.

What we do know, however, is that when a person is not deficient in omega-3 fatty acids and polyphenols, the symptoms of RLS and iron deficiency are typically not a concern. Testing your omega-3 levels can scientifically validate whether you’re getting enough of these vital nutrients to support iron absorption and relieve RLS symptoms.

What Causes Restless Leg Syndrome?

Although the exact cause of RLS is unclear, research points to a strong link between the condition and low iron levels in the brain. Iron plays a crucial role in producing dopamine, a neurotransmitter that helps control muscle movement. Without enough iron in the brain, dopamine levels can drop, causing the miscommunication between your brain and muscles that leads to the uncomfortable sensations in your legs.

This is why treating RLS isn’t just about getting enough iron in your blood—it’s about making sure your brain has access to that iron too. Unfortunately, even if you’re consuming enough iron, your body may not absorb or transport it to the brain efficiently.

Studies show that people with RLS often have reduced iron levels in their cerebrospinal fluid, which indicates a shortage in the brain itself. This brain-specific iron deficiency contributes to the abnormal nerve activity that causes RLS symptoms (Allen et al., 2013).

Why Iron Supplements Alone Don’t Solve the Problem

It’s a common mistake to think that taking more iron supplements will fix iron deficiency. Unfortunately, this approach often wastes both time and money. Why? Because the real issue is not how much iron you’re consuming but how well your body absorbs and uses it.

Iron absorption depends on many factors, including the health of your cell membranes and your body’s inflammation levels. If your omega-3 levels are low, your cell membranes may be stiff, making it harder for nutrients like iron to enter the cells. Without addressing this underlying issue, adding more iron through supplements or infusions is like trying to fill a leaky bucket—it doesn’t work effectively.

This is why I always emphasize improving omega-3 levels first. When you have enough omega-3s and polyphenols, your body can absorb iron much more efficiently, and symptoms of RLS and iron deficiency are far less likely to be an issue.

The Role of Dried Blood Spot Testing

One of the most reliable ways to determine if omega-3 insufficiency is affecting your health is through Dried Blood Spot testing. This simple test removes the guesswork and bias by providing an accurate, scientific measurement of your omega-3 levels.

With just a small drop of blood, this test can reveal if your omega-3 levels are below the recommended range, which is critical for improving iron absorption and relieving RLS symptoms. Many people think they’re consuming enough omega-3s, but testing often shows otherwise. With validated results in hand, you can take targeted steps to address deficiencies and monitor your progress over time.

A Mother’s Story: Solving Iron Deficiency with Omega-3

One day, a concerned mom came to me because her daughter had been struggling with iron deficiency for a long time. Despite eating iron-rich foods and receiving iron infusions, her daughter’s iron levels were still not improving. The infusions were not only costly but also time-consuming and stressful for both of them.

I explained to her that part of the problem might be her daughter’s omega-3 levels. Iron absorption isn’t just about how much iron you consume—it’s also about how well your body can use it. Omega-3s play a crucial role in making cell membranes flexible, which helps iron get into the cells where it’s needed, including the brain.

After using Dried Blood Spot testing, we confirmed that her daughter’s omega-3 levels were far below optimal. I suggested she increase her omega-3 intake using BalanceOil+, a supplement I endorse and it combines omega-3s with polyphenols to maximize absorption and effectiveness. After a few weeks of consistent use, her daughter’s iron levels improved significantly, and she no longer needed iron infusions. The mom was thrilled and amazed by the simple change that made such a big difference.

How Omega-3 and Polyphenols Help Restless Leg Syndrome

When my clients start taking BalanceOil+, something amazing happens. This supplement doesn’t just have omega-3s—it also has polyphenols, which come from unripe olives. These polyphenols protect omega-3s from breaking down and help your body absorb them better.

After testing and using BalanceOil+, many of my clients have reported fewer RLS symptoms. Why? Because the combination of omega-3s and polyphenols helps their body absorb more iron, which calms their nerves and reduces the leg discomfort they feel at night.

What You Can Do

If you’re dealing with RLS or low iron, here’s how you can start feeling better:

1. 1. Get Dried Blood Spot testing: This scientifically validated test measures your omega-3 levels and provides clarity on what your body needs. I can help you get the test done.
   2. Take BalanceOil+: This unique supplement provides omega-3s and polyphenols, which work together to improve your iron absorption and reduce RLS symptoms. I can help you get this product.
   3. Eat iron-rich foods: Include foods like red meat, leafy greens, and beans in your diet. Again, the omega-3s will help your body absorb the iron from these foods better.

Next Steps

Restless Leg Syndrome and iron deficiency can make life harder than it needs to be, but the right nutrition can make a big difference. With Dried Blood Spot testing, you can remove the guesswork and confirm whether omega-3 insufficiency is affecting your health. By addressing deficiencies with omega-3s, polyphenols, and iron-rich foods, you can feel calmer, sleep better, and have more energy.

If you or someone you love struggles with RLS or iron deficiency, remember this: improving your omega-3 levels can significantly impact how your body absorbs iron, especially in the brain, and how you feel overall. However, it’s important to note that not all omega-3 or fish oil supplements are created equal. BalanceOil+ stands out because it combines omega-3s with polyphenols, a unique formula that makes all the difference.

I’ve had clients try other brands, only to find through Dried Blood Spot testing that their omega-3 levels remained insufficient. The proof is in the results—BalanceOil+ consistently delivers what’s needed. So, don’t take shortcuts or assume any omega-3 supplement will do the same. Choose the right supplement for the best outcomes.

Final Thoughts

You may be thinking to yourself, “I’ve lived with RLS and iron deficiencies for years—why am I just now learning about the benefits of combining polyphenols with omega-3s from Robert Ferguson?” The truth is, there is unfortunately a widespread lack of awareness about how polyphenols and omega-3s can address Restless Leg Syndrome (RLS) and iron deficiencies. To provide a clearer picture of why this is the case, I’ve identified seven key factors contributing to this knowledge gap:

1. Focus on Conventional Treatments

• • Traditional medical approaches often focus on symptom management rather than root causes. For RLS, common treatments include iron supplements, dopamine-related medications, or other pharmaceuticals. Similarly, for iron deficiencies, the focus is often solely on increasing dietary iron or prescribing iron infusions. Omega-3s and polyphenols, which work indirectly by enhancing iron absorption and improving cellular health, are less emphasized in mainstream treatments.

2. Limited Physician Training on Nutrition

• • Many healthcare providers receive minimal training in nutrition during medical school, leaving gaps in understanding the role of nutrients like omega-3s and polyphenols in addressing conditions like RLS and iron deficiencies. This knowledge gap can lead to missed opportunities to explore non-pharmaceutical interventions.

3. Nutritional Research Isn’t Always Accessible

• • While there is significant research on omega-3s and polyphenols, the findings often stay within scientific journals and are not widely communicated to the public. Without simplified, relatable messaging, the average person might not realize how these nutrients can help.

4. Bias Toward Quick-Fix Solutions

• • People often prefer fast, easy solutions to health problems, such as a pill or infusion, rather than addressing dietary or lifestyle changes. This mindset may prevent individuals from exploring options like omega-3 and polyphenol supplementation, which require consistency and time to show results.

5. Limited Marketing for Nutritional Approaches

• • Pharmaceutical companies have significant resources to promote medications for conditions like RLS and iron deficiencies. In contrast, omega-3 and polyphenol supplements are marketed less aggressively, and their potential therapeutic effects are often overlooked.

6. Complexity of Nutritional Science

• • The relationship between omega-3s, polyphenols, iron absorption, and RLS is complex. Without clear, digestible information, people may struggle to understand how these nutrients can help.

7. Lack of Routine Testing

• • Tools like Dried Blood Spot testing, which can identify omega-3 insufficiency, are not yet standard practice in healthcare. Without routine testing, deficiencies may go unnoticed, and people may not recognize the connection between their symptoms and nutrient levels.

References

1. 1. Allen, R. P., et al. (2013). Association of Iron Deficiency With Restless Legs Syndrome. American Journal of Hematology. Retrieved from https://onlinelibrary.wiley.com/doi/10.1002/ajh.23397
   2. Frontiers in Neurology (2020). Iron Deficiency Without Anemia in Restless Leg Syndrome. Retrieved from https://www.frontiersin.org/articles/10.3389/fneur.2020.00298/full
   3. Miles, E. A., & Calder, P. C. (2017). Interactions Between Omega-3 Fatty Acids and Iron. Retrieved from https://link.springer.com/chapter/10.1007/978-3-319-40458-5_24
   4. Visioli, F., & Galli, C. (2001). Biological Properties of Olive Oil Polyphenols: Implications in Health and Disease. Journal of Nutritional Biochemistry.
   5. Harris, W. S., et al. (2004). Omega-3 Index as a Risk Factor for Cardiovascular Disease: Validity and Clinical Utility. American Journal of Clinical Nutrition.
   6. Connor, J. R., et al. (2011). Iron and the Brain: Neurodevelopment and Neurodegeneration. Frontiers in Neuroscience.

_______________
Robert Ferguson is a California- and Florida-based single father of two daughters, nutritionist, researcher, best-selling author, speaker, podcast and television host, health advisor, NAACP Image Award Nominee, creator of the Diet Free Life methodology, Chief Nutrition Officer for iCoura Health, and he serves on the Presidential Task Force on Obesity for the National Medical Association. You can e-mail Robert at robert@dietfreelife.com.

🗓️ Schedule a FREE consultation with Robert Ferguson about becoming a client: SCHEDULE FREE CONSULTATION

👉🏽 To order ONLY the BalanceOil+, > CLICK HERE

👉🏽 To order the BalanceOil+ with the BalanceTEST, > CLICK HERE

👉🏽 Watch a free online presentation on the BalanceOil+ and the BalanceTEST: WATCH NOW.